Journal article
Timing and Dose of Upper Limb Motor Intervention After Stroke: A Systematic Review
KS Hayward, SF Kramer, EJ Dalton, GR Hughes, A Brodtmann, L Churilov, G Cloud, D Corbett, L Jolliffe, T Kaffenberger, V Rethnam, V Thijs, N Ward, N Lannin, J Bernhardt
Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021
Abstract
This systematic review aimed to investigate timing, dose, and efficacy of upper limb intervention during the first 6 months poststroke. Three online databases were searched up to July 2020. Titles/abstracts/full-text were reviewed independently by 2 authors. Randomized and nonrandomized studies that enrolled people within the first 6 months poststroke, aimed to improve upper limb recovery, and completed preintervention and postintervention assessments were included. Risk of bias was assessed using Cochrane reporting tools. Studies were examined by timing (recovery epoch), dose, and intervention type. Two hundred and sixty-one studies were included, representing 228 (n=9704 participants) uniq..
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Awarded by National Institutes of Health
Funding Acknowledgements
Drs Hayward, Lannin, and Bernhardt, National Health and Medical Research Council of Australia (Dr Hayward:1088449, Dr Lannin: 1112158, and Dr Bernhardt: 1154904); Drs Lannin and Brodtmann, Heart Foundation of Australia Future Leader Fellowship (Dr Lannin: GNT102055; Dr Brodtmann: GNT100784 and GNT104748); E.J. Dalton, Australian Government Research Training Program Scholarship. Project: Awarded to Dr Hayward from Heart Foundation of Australia and Stroke Foundation of Australia. The Florey Institute of Neuroscience and Mental Health acknowledges the support of the Victorian Government's Operational Infrastructure Support Grant.